I have been running mods for a few months now, without issue. And I dont think I have seen many reports of broken mods ether, beyond the script heavy once, like Kronos and Utility. I also know of a save from Alpha Weekend, thats still working, even after months of mod usage.
The only thing that happens when you remove a mod, is that everything that mod adds, goes away. So unless its a mod that permanetly changes base game stuff (like belt speed), it will take a lot to corrupt a save.
From Offical Discord "- We officially support mods and the modding community." So thats already a thing, its just that the time they have to give us a dev kit, is limited, so we cant do everything yet (mostly c++ stuff, I belive).